In collaboration with the BROAD Institute we complete the exome sequencing for 712 samples of the ITAN collection. These novel data will allow the genetic characterization of the vast majority of the ITAN dataset. We plan to analyze these data in order to identify rare variants in family with high risk. Moreover we will apply…

ITAN foundation won the first place in the funding rating of Italian Autism Foundation (FIA), funded by the #sfidAutismo19. Thanks to this project we will characterize the genetic of 700 more samples through deep sequencing. The collaboration with researchers of University of Trento will help us to improve the knowledge of the genetic bases of…

Transcriptome signatures from discordant sibling pairs reveal changes in peripheral blood immune cell composition in Autism Spectrum Disorder Notwithstanding several research efforts in the past years, robust and replicable molecular signatures for autism spectrum disorders from peripheral blood remain elusive. The available literature on blood transcriptome in ASD suggests that through accurate experimental design it…